Aug 29 2008
Fertility Study: Healthier Babies from Frozen Embryos than Fresh Ones
According to two separate studies presented at a fertility conference of the European Society of Human Reproduction and Embryology in Barcelona, in-vitro fertilization (IVF) and the freezing of embryos does not increase babies’ chances of birth defects or any other medical problems. In fact, scientists have discovered babies born from embryos that are frozen, thawed and then implanted had higher birth weights than babies born from fresh embryos and they were also less likely to be premature.
One study examined over 120 babies born following in-vitro fertilization. These babies were compared to 90 babies born to parents who had fertility problems, but spontaneously conceived while awaiting fertility treatment, as well as 450 babies naturally conceived. This Danish study was done by Dr. Karin Middelburg, of the University Medical Center Groningen in the Netherlands and colleagues. The researchers assessed babies’ brain development after their first six months of life. “When a child is wired right in the brain, he is able to show a wide range of different movements,” said Dr. Middelburg. The results: IVF babies moved just as well as the babies who were born spontaneously to parents awaiting fertility treatments. When the IVF babies were compared to babies naturally conceived in the general population, there were also no difference in abnormal movements. This shows IVF is not the cause of early development problems, according to Dr. Middelburg.
The other Danish study presented at the fertility conference looked at more than 19,000 babies total. Approximately 12,000 of the babies had been born from frozen embryos between 1995 and 2006, while approximately 17,800 of the babies had been born from fresh embryos. The results of this study showed fewer babies born from frozen embryos were admitted to neonatal care units, but the researchers said this was most likely due to a higher rate of multiple births that occur from fresh embryos. Also, pregnancies tended to last slightly longer after a frozen embryo transfer.
Additionally, the study concluded babies born from frozen embryos weighed more at birth than babies born after a fresh embryo transfer; an average of 200 grams bigger! But, this may be because, “Only the very top quality embryos survive the freezing and thawing process,” said Dr. Anja Pinborg, who led the research. Dr. Pinborg continued, “If our results continue to be positive, FER (frozen embryo replacement) can be accepted as a completely safe procedure, which can be used even more frequently than it is currently.”
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A recent press release from The Ohio State University Medical Center urges expectant moms to steer clear of early scheduled C-sections, unless there is a clear medical reason. Early, being defined as, “before completing 39 weeks of pregnancy”. Scheduling an early C-section or induction due to normal third-trimester pregnancy discomforts is not a good reason afterall, even though it may feel that way. Planning an early delivery for visiting family or because your health care provider will be out of town as your due date approaches are not valid reasons, either. Sorry.